首页> FEBS letters> THAP3 recruits SMYD3 to OXPHOS genes and epigenetically promotes mitochondrial respiration in hepatocellular carcinoma.

THAP3 recruits SMYD3 to OXPHOS genes and epigenetically promotes mitochondrial respiration in hepatocellular carcinoma.

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第一作者： Zi-Hao,Wang

第一单位： Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.

作者： Zi-Hao,Wang ^[1] ; Jingyi,Wang ^[2] ; Fuchen,Liu ^[3] ; Sijun,Sun ^[4] ; Quan,Zheng ^[5] ; Xiaotian,Hu ^[6] ; Zihan,Yin ^[2] ; Chengmei,Xie ^[7] ; Haiyan,Wang ^[8] ; Tianshi,Wang ^[9] ; Shengjie,Zhang ^[7] ; Yi-Ping,Wang ^[10]

作者单位： Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. ^[1] Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ^[2] The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Third Affiliated Hospital, Naval Medical University, Shanghai, China. ^[3] Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.;Department of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ^[4] Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, China. ^[5] Department of Gastrointestinal Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ^[6] Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ^[7] Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ^[8] Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, China. ^[9] Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.;Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. ^[10]

关键词 SET and MYND domain‐containing protein 3 THAP domain‐containing 3 histone H3 lysine 4 tri‐methylation liver cancer mitochondrial respiration oxidative phosphorylation