Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria.-论文-万方医学网

第一作者： Kassoum,Kayentao

第一单位： From the Malaria Research and Training Center, Mali International Center of Excellence in Research, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali (K.K., A. Ongoiba, S.D., D.D., A.T., H.T., A. Djiguiba, S. Traore, M.K., A.Z., A. Ouattara, M.D., A. Dolo, A. Djimdé, B.T.); the Malaria Infection Biology and Immunity Section, Laboratory of Immunogenetics, Division of Intramural Research (A.C.P., S.A.H., J.S., H.C., S.L., M.E.P., P.D.C.), and the Biostatistics Research Branch, Division of Clinical Research (Z.H.), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, the Vaccine Research Center (S. Telscher, A.H.I., W.C.A., A.B.M., S.N., B.C.L., L.S., S.P.H., A.J.M., S.V., M.R., J.A.S., J.G.G., K.C., R.A.S.), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, and the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick (J.W.) - all in Maryland; the Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston (P.S., D.E.N.); the Malaria Molecular Diagnostic Laboratory, Department of Laboratory Medicine and Pathology, and the Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle (S.C.M.); and the Max Planck Institute for Infection Biology, Berlin (S.P.).

作者： Kassoum,Kayentao ^[1] ; Aissata,Ongoiba ^[1] ; Anne C,Preston ^[1] ; Sara A,Healy ^[1] ; Zonghui,Hu ^[1] ; Jeff,Skinner ^[1] ; Safiatou,Doumbo ^[1] ; Jing,Wang ^[1] ; Hamidou,Cisse ^[1] ; Didier,Doumtabe ^[1] ; Abdrahamane,Traore ^[1] ; Hamadi,Traore ^[1] ; Adama,Djiguiba ^[1] ; Shanping,Li ^[1] ; Mary E,Peterson ^[1] ; Shinyi,Telscher ^[1] ; Azza H,Idris ^[1] ; William C,Adams ^[1] ; Adrian B,McDermott ^[1] ; Sandeep,Narpala ^[1] ; Bob C,Lin ^[1] ; Leonid,Serebryannyy ^[1] ; Somia P,Hickman ^[1] ; Andrew J,McDougal ^[1] ; Sandra,Vazquez ^[1] ; Matthew,Reiber ^[1] ; Judy A,Stein ^[1] ; Jason G,Gall ^[1] ; Kevin,Carlton ^[1] ; Philipp,Schwabl ^[1] ; Siriman,Traore ^[1] ; Mamadou,Keita ^[1] ; Amatigué,Zéguimé ^[1] ; Adama,Ouattara ^[1] ; M'Bouye,Doucoure ^[1] ; Amagana,Dolo ^[1] ; Sean C,Murphy ^[1] ; Daniel E,Neafsey ^[1] ; Silvia,Portugal ^[1] ; Abdoulaye,Djimdé ^[1] ; Boubacar,Traore ^[1] ; Robert A,Seder ^[1] ; Peter D,Crompton ^[1] ; Mali Malaria mAb Trial Team

作者单位： From the Malaria Research and Training Center, Mali International Center of Excellence in Research, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali (K.K., A. Ongoiba, S.D., D.D., A.T., H.T., A. Djiguiba, S. Traore, M.K., A.Z., A. Ouattara, M.D., A. Dolo, A. Djimdé, B.T.); the Malaria Infection Biology and Immunity Section, Laboratory of Immunogenetics, Division of Intramural Research (A.C.P., S.A.H., J.S., H.C., S.L., M.E.P., P.D.C.), and the Biostatistics Research Branch, Division of Clinical Research (Z.H.), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, the Vaccine Research Center (S. Telscher, A.H.I., W.C.A., A.B.M., S.N., B.C.L., L.S., S.P.H., A.J.M., S.V., M.R., J.A.S., J.G.G., K.C., R.A.S.), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, and the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick (J.W.) - all in Maryland; the Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston (P.S., D.E.N.); the Malaria Molecular Diagnostic Laboratory, Department of Laboratory Medicine and Pathology, and the Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle (S.C.M.); and the Max Planck Institute for Infection Biology, Berlin (S.P.). ^[1]

主题词成年人(Adult);儿童(Child);女(雌)性(Female);人类(Humans);男(雄)性(Male);剂量效应关系, 药物(Dose-Response Relationship, Drug);双盲法(Double-Blind Method);地方病(Endemic Diseases);注射, 皮下(Injections, Subcutaneous);Kaplan-Meiers评估(Kaplan-Meier Estimate);疟疾, 恶性(Malaria, Falciparum);马里(Mali);恶性疟原虫(Plasmodium falciparum);治疗结果(Treatment Outcome);直接观察疗法(Directly Observed Therapy);青年人(Young Adult);中年人(Middle Aged)

DOI 10.1056/NEJMoa2312775

PMID 38669354

发布时间 2024-11-03

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Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria.

The New England journal of medicine

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The New England journal of medicine

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检索历史 清除

Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria.

The New England journal of medicine

相似文献

The New England journal of medicine

相关期刊

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