Recent advances in the discovery and development of drugs targeting the kallikrein-kinin system.

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第一作者： Petra,Wisniewski

第一单位： Individualized Pharmacotherapy, Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany.

作者： Petra,Wisniewski ^[1] ; Tanja,Gangnus ^[1] ; Bjoern B,Burckhardt ^[2]

作者单位： Individualized Pharmacotherapy, Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany. ^[1] Individualized Pharmacotherapy, Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149, Münster, Germany. burckhardt@uni-muenster.de. ^[2]

关键词 B1 receptor B2 receptor Bradykinin Coagulation factor XII Diabetic macular edema Diabetic retinopathy Kallikrein-kinin system Plasma kallikrein Thromboprophylaxis Tissue kallikrein

主题词人类(Humans);血管舒缓素-激肽系统(Kallikrein-Kinin System);药物发现(Drug Discovery);动物(Animals)

DOI 10.1186/s12967-024-05216-5

PMID 38671481

发布时间 2024-04-29

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