CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity.

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作者： Audrey,Flavin ^[1] ; Paniz,Azizi ^[1] ; Natalia,Murataeva ^[1] ; Kyle,Yust ^[1] ; Wenwen,Du ^[1] ; Ruth,Ross ^[2] ; Iain,Greig ^[3] ; Thuy,Nguyen ^[4] ; Yanan,Zhang ^[4] ; Ken,Mackie ^[1] ; Alex,Straiker ^[1]

作者单位： Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences Indiana University, Bloomington, IN 47405, USA. ^[1] Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5G 2C8, Canada. ^[2] Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK. ^[3] Research Triangle Institute, Durham, NC 27709, USA. ^[4]

关键词 JWH018 antidote cannabinoid toxicity overdose synthetic cannabinoid

主题词动物(Animals);人类(Humans);小鼠(Mice);别构调节(Allosteric Regulation);大麻酚类(Cannabinoids);吲哚类(Indoles);受体, 大麻酚, CB1(Receptor, Cannabinoid, CB1)

DOI 10.3390/molecules29081881

PMID 38675703

发布时间 2024-05-16

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