首页> Experimental neurology> Inhibiting the IRAK4/NF-κB/NLRP3 signaling pathway can reduce pyroptosis in hippocampal neurons and seizure episodes in epilepsy.

Inhibiting the IRAK4/NF-κB/NLRP3 signaling pathway can reduce pyroptosis in hippocampal neurons and seizure episodes in epilepsy.

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第一作者： Ting,Zhao

第一单位： Department of Neurology and Basic Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China.

作者： Ting,Zhao ^[1] ; Xuefei,Zhang ^[1] ; Xiaoxiao,Cui ^[1] ; Songxue,Su ^[1] ; Lei,Li ^[1] ; Yanan,Chen ^[1] ; Na,Wang ^[1] ; Lei,Sun ^[1] ; Jianyuan,Zhao ^[2] ; Jiewen,Zhang ^[3] ; Xiong,Han ^[4] ; Jing,Cao ^[5]

作者单位： Department of Neurology and Basic Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China. ^[1] Institute for Developmental and Regenerative Cardiovascular Medicine, MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. Electronic address: zhaojy@vip.163.com. ^[2] Department of Neurology and Basic Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China. Electronic address: zhangjiewen@zzu.edu.cn. ^[3] Department of Neurology and Basic Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China. Electronic address: hanxiong@zzu.edu.cn. ^[4] Department of Neurology and Basic Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China. Electronic address: caojing@zzu.edu.cn. ^[5]

关键词 Epilepsy IRAK4 NF-κB NLRP3 inflammasome Pyroptosis