A high efficiency precision genome editing method with CRISPR in iPSCs.

导出 LinkOut

翻译打印收藏纠错

作者： Avinash,Singh ^[1] ; G Dalton,Smedley ^[1] ; Jamee-Grace,Rose ^[1] ; Kristina,Fredriksen ^[2] ; Ying,Zhang ^[3] ; Ling,Li ^[2] ; Shauna H,Yuan ^[4]

作者单位： Department of Neurology, University of Minnesota, Twin Cities, Minneapolis, MN, USA. ^[1] Graduate Program in Neuroscience, University of Minnesota, Twin Cities, Minneapolis, MN, USA. ^[2] Minnesota Supercomputing Institute, University of Minnesota, Twin Cities, Minneapolis, MN, USA. ^[3] Department of Experimental and Clinical Pharmacology, University of Minnesota, Twin Cities, Minneapolis, MN, USA. ^[4] Department of Neurology, University of Minnesota, Twin Cities, Minneapolis, MN, USA. syuan@umn.edu. ^[5] Graduate Program in Neuroscience, University of Minnesota, Twin Cities, Minneapolis, MN, USA. syuan@umn.edu. ^[6] Minneapolis Veterans Administration Health Care System, Minneapolis, MN, USA. syuan@umn.edu. ^[7]

关键词 CRISPR Gene editing High efficiency Single nucleotide polymorphism iPSC

主题词诱导多能干细胞(Induced Pluripotent Stem Cells);人类(Humans);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)

DOI 10.1038/s41598-024-60766-4

PMID 38688988

发布时间 2024-05-03

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交