The deubiquitinase USP5 promotes cholangiocarcinoma progression by stabilizing YBX1.

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第一作者： Fengling,Ning

第一单位： Department of Pharmacology, School of Pharmacy & Minhang Hospital, Fudan University, Shanghai 201203, China.

作者： Fengling,Ning ^[1] ; Ling,Du ^[1] ; Jiayang,Li ^[1] ; Tiangang,Wu ^[1] ; Jiacheng,Zhou ^[1] ; Zihui,Chen ^[1] ; Xuetao,Hu ^[1] ; Yuai,Zhang ^[1] ; Xin,Luan ^[2] ; Hong,Xin ^[3] ; Chunyan,Yuan ^[4] ; Xuemei,Zhang ^[5]

作者单位： Department of Pharmacology, School of Pharmacy & Minhang Hospital, Fudan University, Shanghai 201203, China. ^[1] Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. ^[2] Department of Pharmacology, School of Pharmacy & Minhang Hospital, Fudan University, Shanghai 201203, China. Electronic address: xinhong@fudan.edu.cn. ^[3] Department of Pharmacology, School of Pharmacy & Minhang Hospital, Fudan University, Shanghai 201203, China. Electronic address: yuan_chunyan@fudan.edu.cn. ^[4] Department of Pharmacology, School of Pharmacy & Minhang Hospital, Fudan University, Shanghai 201203, China. Electronic address: xuemzhang@fudan.edu.cn. ^[5]

关键词 Cholangiocarcinoma Deubiquitinatinase USP5 YBX1

主题词人类(Humans);胆管上皮癌(Cholangiocarcinoma);胆管肿瘤(Bile Duct Neoplasms);动物(Animals);细胞增殖(Cell Proliferation);小鼠(Mice);疾病恶化(Disease Progression);细胞系, 肿瘤(Cell Line, Tumor);小鼠, 裸(Mice, Nude);细胞运动(Cell Movement);Y盒结合蛋白质1(Y-Box-Binding Protein 1);上皮-间质转化(Epithelial-Mesenchymal Transition);泛素化(Ubiquitination);小鼠, 近交BALB C(Mice, Inbred BALB C);男(雄)性(Male);内肽酶类(Endopeptidases);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);女(雌)性(Female)

DOI 10.1016/j.lfs.2024.122674

PMID 38692507

发布时间 2024-05-29

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Life sciences

2024年348卷

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The deubiquitinase USP5 promotes cholangiocarcinoma progression by stabilizing YBX1.

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The deubiquitinase USP5 promotes cholangiocarcinoma progression by stabilizing YBX1.

Life sciences

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