Biochemical, Biomarker, and Behavioral Characterization of the Grn<sup>R493X</sup> Mouse Model of Frontotemporal Dementia.
第一作者:
Denise M,Smith
第一单位:
Division of Geriatric Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA.;Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, USA.;Institute for Translational Neuroscience, Saint Louis University, St. Louis, USA.
作者:
主题词
动物(Animals);额颞叶痴呆(Frontotemporal Dementia);疾病模型, 动物(Disease Models, Animal);行为, 动物(Behavior, Animal);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);杂合子(Heterozygote);男(雄)性(Male);脑(Brain);磷酰化(Phosphorylation);溶酶体(Lysosomes);DNA结合蛋白质类(DNA-Binding Proteins);基因敲入技术(Gene Knock-In Techniques)
DOI
10.1007/s12035-024-04190-9
PMID
38696065
发布时间
2024-11-23
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Molecular neurobiology
9708-9722页
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