A Preclinical Trial Protocol Using an Ovine Model to Assess Scaffold Implant Biomaterials for Repair of Critical-Sized Mandibular Defects.

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作者： Hai,Xin ^[1] ; Ben M,Ferguson ^[2] ; Boyang,Wan ^[3] ; D S Abdullah,Al Maruf ^[3] ; William T,Lewin ^[1] ; Kai,Cheng ^[2] ; Hedi V,Kruse ^[4] ; David,Leinkram ^[5] ; Krishnan,Parthasarathi ^[6] ; Innes K,Wise ^[1] ; Catriona,Froggatt ^[7] ; Jeremy M,Crook ^[4] ; David R,McKenzie ^[5] ; Qing,Li ^[8] ; Jonathan R,Clark ^[1]

作者单位： Integrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia. ^[1] Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia. ^[2] School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Darlington, NSW 2006, Australia. ^[3] Arto Hardy Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia. ^[4] Sarcoma and Surgical Research Centre, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia. ^[5] School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia. ^[6] Royal Prince Alfred Institute of Academic Surgery, Sydney Local Health District, Camperdown, NSW 2050, Australia. ^[7] School of Physics, Faculty of Science, The University of Sydney, Syndey, NSW 2006, Australia. ^[8] Laboratory Animal Services, The University of Sydney, Camperdown, NSW 2050, Australia. ^[9] Intelligent Polymer Research Institute, AIIM Facility, The University of Wollongong, Wollongong, NSW 2519, Australia. ^[10] Centre for Advanced Materials Technology, The University of Sydney, Darlington, NSW 2006, Australia. ^[11]

关键词 3D printing bone tissue engineering mandibular defect ossification ovine model poly ether ketone scaffolds

主题词动物(Animals);绵羊(Sheep);下颌骨(Mandible);生物相容性材料(Biocompatible Materials);组织支架(Tissue Scaffolds);有限元分析(Finite Element Analysis);骨生成(Osteogenesis)

DOI 10.1021/acsbiomaterials.4c00262

PMID 38696332

发布时间 2024-06-12

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ACS biomaterials science & engineering

2024年10卷5期

2863-2879页

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A Preclinical Trial Protocol Using an Ovine Model to Assess Scaffold Implant Biomaterials for Repair of Critical-Sized Mandibular Defects.

ACS biomaterials science & engineering

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A Preclinical Trial Protocol Using an Ovine Model to Assess Scaffold Implant Biomaterials for Repair of Critical-Sized Mandibular Defects.

ACS biomaterials science & engineering

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ACS biomaterials science & engineering

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