A Membrane-Targeting Aggregation-Induced Emission Probe for Monitoring Lipid Droplet Dynamics in Ischemia/Reperfusion-Induced Cardiomyocyte Ferroptosis.

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作者： Yihui,Wang ^[1] ; Yuan,Song ^[2] ; Lingling,Xu ^[3] ; Wuqi,Zhou ^[1] ; Wenyuan,Wang ^[2] ; Qiaofeng,Jin ^[3] ; Yuji,Xie ^[1] ; Junmin,Zhang ^[2] ; Jing,Liu ^[3] ; Wenqian,Wu ^[1] ; He,Li ^[2] ; Le,Liang ^[3] ; Jing,Wang ^[1] ; Yali,Yang ^[2] ; Xiongwen,Chen ^[3] ; Shuping,Ge ^[1] ; Tang,Gao ^[2] ; Li,Zhang ^[3] ; Mingxing,Xie ^[1]

作者单位： Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ^[1] Clinical Research Center for Medical Imaging, No. 1277 Jiefang Avenue, Wuhan, Hubei, 430022, China. ^[2] Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China. ^[3] The Institute of Advanced Studies Wuhan University, Wuhan, 430072, China. ^[4] Department of Biopharmaceuticals & Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300052, China. ^[5] Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, 300052, China. ^[6] Drexel University College of Medicine and St. Christopher's Hospital for Children, 3601 A Street, Philadelphia, PA, 19134, USA. ^[7] Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, 518029, China. ^[8]

关键词 aggregation‐induced emissions ferroptosis lipid droplet imaging lipophagy myocardial ischemia/reperfusion injury

主题词动物(Animals);小鼠(Mice);肌细胞, 心脏(Myocytes, Cardiac);心肌再灌注损伤(Myocardial Reperfusion Injury);疾病模型, 动物(Disease Models, Animal);男(雄)性(Male);分子动力学模拟(Molecular Dynamics Simulation);脂质过氧化作用(Lipid Peroxidation)

DOI 10.1002/advs.202309907

PMID 38696589

发布时间 2024-07-12

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2024年11卷26期

e2309907页

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A Membrane-Targeting Aggregation-Induced Emission Probe for Monitoring Lipid Droplet Dynamics in Ischemia/Reperfusion-Induced Cardiomyocyte Ferroptosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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A Membrane-Targeting Aggregation-Induced Emission Probe for Monitoring Lipid Droplet Dynamics in Ischemia/Reperfusion-Induced Cardiomyocyte Ferroptosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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