Aberrant CD8<sup>+</sup>T cells drive reproductive dysfunction in female mice with elevated IFN-γ levels.

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第一作者： Enitome E,Bafor

第一单位： Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, United States.

作者： Enitome E,Bafor ^[1] ; Rebecca A,Erwin-Cohen ^[1] ; Toni,Martin ^[1] ; Clayton,Baker ^[2] ; Adrienne E,Kimmel ^[3] ; Olivier,Duverger ^[1] ; John M,Fenimore ^[4] ; Meredith,Ramba ^[1] ; Thea,Spindel ^[1] ; Megan M,Hess ^[1] ; Michael,Sanford ^[1] ; Vanja,Lazarevic ^[1] ; Bérénice A,Benayoun ^[5] ; Howard A,Young ^[2] ; Julio C,Valencia ^[3]

作者单位： Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, United States. ^[1] Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, United States. ^[2] Molecular and Computational Biology Department, University of Southern California, Dornsife College of Letters, Arts and Sciences, Los Angeles, CA, United States. ^[3] Craniofacial Anomalies and Regeneration Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, United States. ^[4] Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States. ^[5]

关键词 CD8+ T cells hypophysitis implantation failure interferon-gamma (IFN-γ)luteinization defect pregnancy prolactin deficiency tissue-resident memory