<i>In Vivo</i> Delivery of Spherical and Cylindrical <i>In Vitro</i> Reconstituted Virus-like Particles Containing the Same Self-Amplifying mRNA.

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作者： Sweta,Karan ^[1] ; Ana Luisa,Durán-Meza ^[2] ; Abigail,Chapman ^[3] ; Cheylene,Tanimoto ^[4] ; Soo Khim,Chan ^[4] ; Charles M,Knobler ^[4] ; William M,Gelbart ^[5] ; Nicole F,Steinmetz ^[1]

作者单位： Department of NanoEngineering, University of California San Diego, La Jolla, California 92093, United States. ^[1] Center for Nano-ImmunoEngineering, University of California San Diego, La Jolla, California 92093, United States. ^[2] Shu and K. C. Chien and Peter Farrell Collaboratory, University of California San Diego, La Jolla, California 92093, United States. ^[3] Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States. ^[4] California NanoSystems Institute, University of California, Los Angeles, California 90095, United States. ^[5] UCLA Molecular Biology Institute, University of California, Los Angeles, California 90095, United States. ^[6] Institute for Materials Discovery and Design, University of California San Diego, La Jolla, California 92093, United States. ^[7] Department of Bioengineering, University of California San Diego, La Jolla, California 92093, United States. ^[8] Department of Radiology, University of California San Diego, La Jolla, California 92093, United States. ^[9] Moores Cancer Center, University of California San Diego, La Jolla, California 92093, United States. ^[10] Center for Engineering in Cancer, Institute for Engineering in Medicine, University of California, San Diego, La Jolla, California 92093, United States. ^[11]

关键词 Nodamura replicon cowpea chlorotic mottle virus (CCMV)mRNA vaccine plant virus-like particles (VLPs)self-amplifying mRNA tobacco mosaic virus (TMV)