Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem-Cell Transplantation in Patients With Myelodysplastic Syndromes.
作者:
Cristina Astrid,Tentori [1]
;
Caterina,Gregorio [2]
;
Marie,Robin [3]
;
Nico,Gagelmann [4]
;
Carmelo,Gurnari [5]
;
Somedeb,Ball [6]
;
Juan Carlos,Caballero Berrocal [7]
;
Luca,Lanino [1]
;
Saverio,D'Amico [8]
;
Marta,Spreafico [9]
;
Giulia,Maggioni [1]
;
Erica,Travaglino [10]
;
Elisabetta,Sauta [8]
;
Manja,Meggendorfer [11]
;
Lin-Pierre,Zhao [3]
;
Alessia,Campagna [1]
;
GenoMed4All, Synthema, GESMD, FISIM, and EuroBloodNET [8]
;
Victor,Savevski [1]
;
Armando,Santoro [12]
;
Najla,Al Ali [12]
;
David,Sallman [13]
;
Francesc,Sole [14]
;
Guillermo,Garcia-Manero [15]
;
Ulrich,Germing [4]
;
Nicolaus,Kroger [16]
;
Shahram,Kordasti [17]
;
Valeria,Santini [18]
;
Guillermo,Sanz [11]
;
Wolfgang,Kern [19]
;
Uwe,Platzbecker [7]
;
Maria,Diez-Campelo [20]
;
Jaroslaw P,Maciejewski [3]
;
Lionel,Ades [3]
;
Pierre,Fenaux [11]
;
Torsten,Haferlach [21]
;
Amer M,Zeidan [22]
;
Gastone,Castellani [12]
;
Rami,Komrokji [23]
;
Francesca,Ieva [1]
;
Matteo Giovanni,Della Porta ;
GenoMed4all and Synthema Consortiums
作者单位:
Humanitas Clinical and Research Center-IRCCS, Milan, Italy.;Department of Biomedical Sciences, Humanitas University, Milan, Italy.
[1]
Department of Mathematics, MOX-Modelling and Scientific Computing Laboratory, Politecnico di Milano, Milano, Italy.;Biostatistics Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.;Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet, Stockholm, Sweden.
[2]
Department of Hematology and Bone Marrow Transplantation, Hôpital Saint-Louis/Assistance Publique-Hôpitaux de Paris (AP-HP)/University Paris 7, Paris, France.
[3]
University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[4]
Hematology, Policlinico Tor Vergata & Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
[5]
Vanderbilt University School of Medicine; Vanderbilt-Ingram Cancer Center, Nashville, TN.
[6]
Hematology Department, Hospital Universitario de Salamanca, Salamanca, Spain.
[7]
Humanitas Clinical and Research Center-IRCCS, Milan, Italy.
[8]
Mathematical Institute, Leiden University, Leiden, the Netherlands.
[9]
IRCCS Polilcinico San Matteo, Pavia, Italy.
[10]
MLL Munich Leukemia Laboratory, Munich, Germany.
[11]
Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL.
[12]
Institut de Recerca Contra la Leucèmia Josep Carreras, Barcelona, Spain.
[13]
The University of Texas MD Anderson Cancer Center, Houston, TX.
[14]
Department of Hematology, Oncology, and Clinical Immunology, Heinrich-Heine-University, University Clinic, Düsseldorf, Germany.
[15]
Haematology, Guy's Hospital & Comprehensive Cancer Centre, King's College, London, United Kingdom.;Hematology Department & Stem Cell Transplant Unit, DISCLIMO-Università Politecnica delle Marche, Ancona, Italy.
[16]
MDS Unit, Azienda Ospedaliero-Universitaria Careggi & University of Florence, Florence, Italy.
[17]
Hematology, Hospital Universitario La Fe, Valencia, Spain.
[18]
Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.
[19]
Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH.
[20]
Section of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Cancer Center, New Haven, CT.
[21]
National Institute of Nuclear Physics (INFN), Bologna, Italy.;Experimental, Diagnostic and Specialty Medicine-DIMES, Bologna, Italy.
[22]
Department of Mathematics, MOX-Modelling and Scientific Computing Laboratory, Politecnico di Milano, Milano, Italy.;HDS, Health Data Science Center, Human Technopole, Milan, Italy.
[23]
主题词
人类(Humans);骨髓增生异常综合征(Myelodysplastic Syndromes);造血干细胞移植(Hematopoietic Stem Cell Transplantation);中年人(Middle Aged);男(雄)性(Male);回顾性研究(Retrospective Studies);女(雌)性(Female);老年人(Aged);移植, 同种(Transplantation, Homologous);成年人(Adult);时间因素(Time Factors);决策支持系统, 临床(Decision Support Systems, Clinical);基因组学(Genomics);决策支持技术(Decision Support Techniques);危险性评估(Risk Assessment);青年人(Young Adult)
DOI
10.1200/JCO.23.02175
PMID
38723212
发布时间
2024-10-03
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Journal of clinical oncology
Journal of clinical oncology
2873-2886页
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