The landscape of cancer-rewired GPCR signaling axes.

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第一作者： Chakit,Arora

第一单位： Laboratorio di Biologia Bio@SNS, Scuola Normale Superiore, Piazza dei Cavalieri 7, 56126 Pisa, Italy.

作者： Chakit,Arora ^[1] ; Marin,Matic ^[1] ; Luisa,Bisceglia ^[1] ; Pierluigi,Di Chiaro ^[2] ; Natalia,De Oliveira Rosa ^[1] ; Francesco,Carli ^[1] ; Lauren,Clubb ^[3] ; Lorenzo Amir,Nemati Fard ^[1] ; Giorgos,Kargas ^[1] ; Giuseppe R,Diaferia ^[2] ; Ranka,Vukotic ^[4] ; Luana,Licata ^[5] ; Guanming,Wu ^[6] ; Gioacchino,Natoli ^[2] ; J Silvio,Gutkind ^[7] ; Francesco,Raimondi ^[8]

作者单位： Laboratorio di Biologia Bio@SNS, Scuola Normale Superiore, Piazza dei Cavalieri 7, 56126 Pisa, Italy. ^[1] Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milano, Italy. ^[2] Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA. ^[3] Azienda Ospedaliero-Universitaria Pisana, Via Roma, 67, 56126 Pisa, Italy. ^[4] Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy. ^[5] Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA. ^[6] Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: sgutkind@health.ucsd.edu. ^[7] Laboratorio di Biologia Bio@SNS, Scuola Normale Superiore, Piazza dei Cavalieri 7, 56126 Pisa, Italy; Laboratorio di Biologia Bio@SNS, Scuola Normale Superiore, Piazza dei Cavalieri 7, 56126 Pisa, Italy. Electronic address: francesco.raimondi@sns.it. ^[8]

关键词 GPCR cancer cancer cell lines cell-cell communication drug repurposing personalized medicine signaling network survival analysis transcriptomics

主题词人类(Humans);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);肿瘤(Neoplasms);信号传导(Signal Transduction);配体(Ligands);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic)

DOI 10.1016/j.xgen.2024.100557

PMID 38723607

发布时间 2024-05-24

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Cell genomics

2024年4卷5期

100557页

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The landscape of cancer-rewired GPCR signaling axes.

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The landscape of cancer-rewired GPCR signaling axes.

Cell genomics

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Cell genomics

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