Prediction of anticancer drug sensitivity using an interpretable model guided by deep learning.

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第一作者： Weixiong,Pang

第一单位： College of Information Technology, Shanghai Ocean University, Hucheng Ring Road, Shanghai, China.;Key Laboratory of Fisheries Information Ministry of Agriculture, Shanghai, China.

作者： Weixiong,Pang ^[1] ; Ming,Chen ^[1] ; Yufang,Qin ^[2]

作者单位： College of Information Technology, Shanghai Ocean University, Hucheng Ring Road, Shanghai, China.;Key Laboratory of Fisheries Information Ministry of Agriculture, Shanghai, China. ^[1] College of Information Technology, Shanghai Ocean University, Hucheng Ring Road, Shanghai, China. yfqin@shou.edu.cn.;Key Laboratory of Fisheries Information Ministry of Agriculture, Shanghai, China. yfqin@shou.edu.cn. ^[2]

关键词 Biological pathway Deep neural networks Drug sensitivity Interpretability model

主题词人类(Humans);抗肿瘤药(Antineoplastic Agents);肿瘤(Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);DNA拷贝数变异(DNA Copy Number Variations);计算生物学(Computational Biology)

DOI 10.1186/s12859-024-05669-x

PMID 38724920

发布时间 2024-05-12

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准确一般字义偏差语意偏离译文作用小提交