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PML restrains p53 activity and cellular senescence in clear cell renal cell carcinoma.

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第一作者： Matilde,Simoni

第一单位： Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.

作者： Matilde,Simoni ^[1] ; Chiara,Menegazzi ^[1] ; Cristina,Fracassi ^[1] ; Claudia C,Biffi ^[2] ; Francesca,Genova ^[3] ; Nazario Pio,Tenace ^[4] ; Roberta,Lucianò ^[4] ; Andrea,Raimondi ^[5] ; Carlo,Tacchetti ^[6] ; James,Brugarolas ^[7] ; Davide,Mazza ^[5] ; Rosa,Bernardi ^[8]

作者单位： Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy. ^[1] Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.;Medical Advisor, Sanofi, Milan, Italy. ^[2] Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy. ^[3] Department of Pathology, IRCCS San Raffaele Scientific Institute, Milan, Italy. ^[4] Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy. ^[5] Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.;Universita' Vita-Salute San Raffaele, Milan, Italy. ^[6] Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Department of Internal Medicine, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[7] Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy. bernardi.rosa@hsr.it. ^[8]

关键词 Arsenic Trioxide PML Senescence ccRCC p53