Activation of secondary metabolite gene clusters in Chaetomium olivaceum via the deletion of a histone deacetylase.

导出 OA

翻译打印收藏纠错

第一作者： Peipei,Zhao

第一单位： Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250103, Shandong, China.

作者： Peipei,Zhao ^[1] ; Shengling,Cao ^[1] ; Jiahui,Wang ^[1] ; Jiaying,Lin ^[1] ; Yunzeng,Zhang ^[2] ; Chengwei,Liu ^[3] ; Hairong,Liu ^[1] ; Qingqing,Zhang ^[1] ; Mengmeng,Wang ^[1] ; Yiwei,Meng ^[1] ; Xin,Yin ^[1] ; Jun,Qi ^[1] ; Lixin,Zhang ^[1] ; Xuekui,Xia ^[4]

作者单位： Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250103, Shandong, China. ^[1] Department of Thoracic Surgery, Shandong Public Health Clinical Center, Jinan, 250013, Shandong, China. ^[2] Key Laboratory for Enzyme and Enzyme-Like Material Engineering of Heilongjiang, College of Life Science, Northeast Forestry University, Harbin, 150040, Heilongjiang, China. ^[3] State Key Laboratory of Bioreactor Engineering, School of Biotechnology, East China University of Science and Technology (ECUST), Shanghai, 200237, China. ^[4] Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250103, Shandong, China. xiaxk@sdas.org. ^[5]

关键词 Chaetomium olivaceum Biosynthetic gene clusters Epigenetic regulation HDAC Polyketide synthase