Blockade of the ADAM8-Fra-1 complex attenuates neuroinflammation by suppressing the Map3k4/MAPKs axis after spinal cord injury.

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第一作者： Zhanyang,Qian

第一单位： Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.;Department of Orthopedics, Zhongda Hospital of Southeast University, Nanjing, China.

作者： Zhanyang,Qian ^[1] ; Rulin,Li ^[2] ; Tianyu,Zhao ^[2] ; Kunxin,Xie ^[3] ; PengFei,Li ^[4] ; Guangshen,Li ^[5] ; Na,Shen ^[6] ; Jiamin,Gong ^[6] ; Xin,Hong ^[7] ; Lei,Yang ^[8] ; Haijun,Li ^[9]

作者单位： Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.;Department of Orthopedics, Zhongda Hospital of Southeast University, Nanjing, China. ^[1] Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.;School of Postgraduate, Dalian Medical University, Dalian, China. ^[2] Key Laboratory of Human Functional Genomics of Jiangsu Province, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, China. ^[3] Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.;School of Postgraduate, Nanjing University of Chinese Medicine, Nanjing, China. ^[4] Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China. ^[5] School of Basic Medicine, Nanjing Medical University, Nanjing, China. ^[6] Department of Orthopedics, Zhongda Hospital of Southeast University, Nanjing, China. ^[7] Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China. leiyang@njmu.edu.cn. ^[8] Department of Orthopedics, Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China. 13901436563@139.com. ^[9]

关键词 ADAM8 Fra-1 Map3k4 Microglia Neuroinflammation Spinal cord injury