Region-specific and age-related differences in astrocytes in the human brain.

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第一作者： Jodie H K,Man

第一单位： Department of Child Neurology, Amsterdam Leukodystrophy Center, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Molecular and Cellular Mechanisms, Amsterdam Neuroscience, Amsterdam, the Netherlands.

作者： Jodie H K,Man ^[1] ; Marjolein,Breur ^[1] ; Charlotte A G H,van Gelder ^[2] ; Gabriella,Marcon ^[3] ; Emanuela,Maderna ^[4] ; Giorgio,Giaccone ^[4] ; Maarten,Altelaar ^[2] ; Marjo S,van der Knaap ^[5] ; Marianna,Bugiani ^[6]

作者单位： Department of Child Neurology, Amsterdam Leukodystrophy Center, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Molecular and Cellular Mechanisms, Amsterdam Neuroscience, Amsterdam, the Netherlands. ^[1] Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; Netherlands Proteomics Center, Utrecht, the Netherlands. ^[2] Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy; DAME, University of Udine, Udine, Italy. ^[3] Division of Neurology 5 - Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. ^[4] Department of Child Neurology, Amsterdam Leukodystrophy Center, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Molecular and Cellular Mechanisms, Amsterdam Neuroscience, Amsterdam, the Netherlands; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. ^[5] Department of Pathology, Amsterdam UMC, Amsterdam, the Netherlands. Electronic address: m.bugiani@amsterdamumc.nl. ^[6]

关键词 Aging Astrocyte heterogeneity Human brain Mass spectrometry-based proteomics