Rictor/mTORC2 signalling contributes to renal vascular endothelial-to-mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3-mediated mitophagy.

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作者： Dengyuan,Feng ^[1] ; Zeping,Gui ^[1] ; Zhen,Xu ^[2] ; Jianjian,Zhang ^[1] ; Bin,Ni ^[3] ; Zijie,Wang ^[1] ; Jiawen,Liu ^[2] ; Shuang,Fei ^[1] ; Hao,Chen ^[1] ; Li,Sun ^[1] ; Min,Gu ^[1] ; Ruoyun,Tan ^[1]

作者单位： Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ^[1] Department of Urology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China. ^[2] Department of Urology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China. ^[3]

关键词 Rictor/mTORC2 mitophagy renal allograft interstitial fibrosis vascular endothelial cells

主题词动物(Animals);小鼠(Mice);膜蛋白质类(Membrane Proteins);人类(Humans);肾移植(Kidney Transplantation);纤维化(Fibrosis);信号传导(Signal Transduction);男(雄)性(Male);线粒体蛋白质类(Mitochondrial Proteins);肾(Kidney);小鼠, 近交C57BL(Mice, Inbred C57BL);疾病模型, 动物(Disease Models, Animal);原癌基因蛋白质类(Proto-Oncogene Proteins)

DOI 10.1002/ctm2.1686

PMID 38769658

发布时间 2024-05-22

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Clinical and translational medicine

2024年14卷5期

e1686页

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Rictor/mTORC2 signalling contributes to renal vascular endothelial-to-mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3-mediated mitophagy.

Clinical and translational medicine

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Clinical and translational medicine

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Rictor/mTORC2 signalling contributes to renal vascular endothelial-to-mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3-mediated mitophagy.

Clinical and translational medicine

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Clinical and translational medicine

相关期刊

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