Gprc5a is a novel parathyroid hormone-inducible gene and negatively regulates osteoblast proliferation and differentiation.

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第一作者： Chisato,Sampei

第一单位： Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Science, Tokyo University of Science, Noda, Chiba, Japan.

作者： Chisato,Sampei ^[1] ; Kosuke,Kato ^[1] ; Yasuhiro,Arasaki ^[1] ; Yuta,Kimura ^[1] ; Takuto,Konno ^[1] ; Kanon,Otsuka ^[1] ; Yukihiro,Kohara ^[1] ; Masaki,Noda ^[2] ; Yoichi,Ezura ^[3] ; Tadayoshi,Hayata ^[4]

作者单位： Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Science, Tokyo University of Science, Noda, Chiba, Japan. ^[1] Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.;Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan. ^[2] Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan.;Department of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.;Department of Occupational Therapy, Faculty of Health and Medical Science, Teikyo Heisei University, Toshima-ku, Japan. ^[3] Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Science, Tokyo University of Science, Noda, Chiba, Japan.;Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo, Japan. ^[4]

关键词 Gprc5a MC3T3‐E1 osteoblast osteoporosis parathyroid hormone (PTH)teriparatide