NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.

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作者： Ann E,Tollefson ^[1] ; Anna B,Cline-Smith ^[1] ; Jacqueline F,Spencer ^[1] ; Dawn M,Reyna ^[2] ; Elke,Lipka ^[2] ; Karoly,Toth ^[1]

作者单位： Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, USA. ^[1] TSRL, Inc., Ann Arbor, Michigan, USA. ^[2]

关键词 adenovirus animal model antiviral in vivo prodrug

主题词动物(Animals);抗病毒药(Antiviral Agents);药物前体(Prodrugs);人类(Humans);金仓鼠(Mesocricetus);胞嘧啶(Cytosine);腺病毒, 人(Adenoviruses, Human);腺病毒感染, 人(Adenovirus Infections, Human);疾病模型, 动物(Disease Models, Animal);仓鼠亚科(Cricetinae);投药, 口服(Administration, Oral)

DOI 10.1128/aac.00489-24

PMID 38775484

发布时间 2024-11-23

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Antimicrobial agents and chemotherapy

2024年68卷7期

e0048924页

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NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

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NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

相关期刊

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