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Covalent targeted radioligands potentiate radionuclide therapy.

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作者: Xi-Yang,Cui [1] ; Zhu,Li [2] ; Ziren,Kong [3] ; Yu,Liu [4] ; Hao,Meng [1] ; Zihao,Wen [2] ; Changlun,Wang [1] ; Junyi,Chen [1] ; Mengxin,Xu [1] ; Yiyan,Li [1] ; Jingyue,Gao [2] ; Wenjia,Zhu [1] ; Zhixin,Hao [1] ; Li,Huo [5] ; Shaoyan,Liu [5] ; Zhi,Yang [5] ; Zhibo,Liu [4]
作者单位: Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, P. R. China. [1] Changping Laboratory, Beijing, P. R. China. [2] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Peking University Cancer Hospital and Institute, Beijing, P. R. China. [3] Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China. [4] Department of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine and State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China. [5] Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, P. R. China. zbliu@pku.edu.cn. [6] Changping Laboratory, Beijing, P. R. China. zbliu@pku.edu.cn. [7] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Peking University Cancer Hospital and Institute, Beijing, P. R. China. zbliu@pku.edu.cn. [8] Peking University-Tsinghua University Center for Life Sciences, Peking University, Beijing, P. R. China. zbliu@pku.edu.cn. [9]
DOI 10.1038/s41586-024-07461-6
PMID 38778111
发布时间 2024-06-26
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