Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics.-论文-万方医学网

第一作者： Brie,Wamsley

第一单位： Program in Neurobehavioral Genetics and Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.;Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

作者： Brie,Wamsley ^[1] ; Lucy,Bicks ^[2] ; Yuyan,Cheng ^[3] ; Riki,Kawaguchi ^[3] ; Diana,Quintero ^[3] ; Michael,Margolis ^[4] ; Jennifer,Grundman ^[4] ; Jianyin,Liu ^[3] ; Shaohua,Xiao ^[3] ; Natalie,Hawken ^[4] ; Samantha,Mazariegos ^[3] ; Daniel H,Geschwind ^[5]

作者单位： Program in Neurobehavioral Genetics and Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.;Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. ^[1] Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.;Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. ^[2] Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. ^[3] Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. ^[4] Program in Neurobehavioral Genetics and Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.;Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.;Department of Psychiatry, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.;Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. ^[5]

医学主题词女(雌)性(Female);人类(Humans);男(雄)性(Male);星形细胞(Astrocytes);脑(Brain);染色质(Chromatin);基因调控网络(Gene Regulatory Networks);疾病遗传易感性(Genetic Predisposition to Disease);基因组学(Genomics);中间神经元(Interneurons);小神经胶质细胞(Microglia);神经元(Neurons);少突神经胶质(Oligodendroglia);序列分析, RNA(Sequence Analysis, RNA);单细胞分析(Single-Cell Analysis);儿童, 学龄前(Child, Preschool);儿童(Child);青少年(Adolescent);青年人(Young Adult);成年人(Adult);中年人(Middle Aged)

DOI 10.1126/science.adh2602

PMID 38781372

发布时间 2025-09-25

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Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics.

Science (New York, N.Y.)

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Molecular cascades and cell type-specific signatures in ASD revealed by single-cell genomics.

Science (New York, N.Y.)

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同项目论文

Science (New York, N.Y.)

相关期刊

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