Expression of G2019S LRRK2 in Rat Primary Astrocytes Mediates Neurotoxicity and Alters the Dopamine Synthesis Pathway in N27 Cells via Astrocytic Proinflammatory Cytokines and Neurotrophic Factors.

导出 OA

翻译打印收藏纠错

作者： Dong Hwan,Ho ^[1] ; Hyejung,Kim ^[1] ; Daleum,Nam ^[1] ; Mi Kyoung,Seo ^[2] ; Sung Woo,Park ^[2] ; Ilhong,Son ^[3]

作者单位： InAm Neuroscience Research Center, Sanbon Medical Center, College of Medicine, Wonkwang University, 321, Sanbon-ro, Gunpo-si 15865, Republic of Korea. ^[1] Paik Institute for Clinical Research, Inje University, Busan-si 47392, Republic of Korea. ^[2] Department of Convergence Biomedical Science, Inje University College of Medicine, Busan-si 47392, Republic of Korea. ^[3] Department of Neurology, Sanbon Medical Center, College of Medicine, Wonkwang University, 321, Sanbon-ro, Gunpo-si 15865, Republic of Korea. ^[4]

关键词 Parkinson’s disease astrocyte dopamine synthesis pathway leucine-rich repeat kinase 2 (LRRK2)neuroinflammation neurotrophic factor

DOI 10.3390/cimb46050263

PMID 38785531

发布时间 2024-05-26

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交