SKGQA, a Peptide Derived from the ANA/BTG3 Protein, Cleaves Amyloid-β with Proteolytic Activity.

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作者： Yusuke,Hatakawa ^[1] ; Rina,Nakamura ^[2] ; Toshifumi,Akizawa ^[2] ; Motomi,Konishi ^[3] ; Akira,Matsuda ^[4] ; Tomoyuki,Oe ^[1] ; Motoaki,Saito ^[5] ; Fumiaki,Ito ^[6]

作者单位： Department of Bio-Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aramaki-Aoba, Aoba-ku, Sendai 980-8578, Miyagi, Japan. ^[1] O-Force Co., Ltd., 3454 Irino Kuroshio-cho, Hata-gun 789-1931, Kochi, Japan.;Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, Kochi, Japan. ^[2] Department of Integrative Pharmacy, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata 573-0101, Osaka, Japan. ^[3] Laboratory of Medicinal and Biochemical Analysis, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hirokoshinkai, Kure 737-0112, Hiroshima, Japan. ^[4] Department of Pharmacology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, Kochi, Japan. ^[5] O-Force Co., Ltd., 3454 Irino Kuroshio-cho, Hata-gun 789-1931, Kochi, Japan.;The Institute of Prophylactic Pharmacology, 1-58, Rinku-oraikita, Izumisano 598-8531, Osaka, Japan. ^[6]

关键词 ANA-SA5 ANA-TA9 Alzheimer’s disease Catalytide JAL-TA9 amyloid-β neurodegenerative disease peptide drug proteolytic peptide serine proteases

主题词人类(Humans);阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);细胞系, 肿瘤(Cell Line, Tumor);肽碎片(Peptide Fragments);肽类(Peptides);细胞周期蛋白质类(Cell Cycle Proteins)

DOI 10.3390/biom14050586

PMID 38785993

发布时间 2024-09-11

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Biomolecules

2024年14卷5期

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SKGQA, a Peptide Derived from the ANA/BTG3 Protein, Cleaves Amyloid-β with Proteolytic Activity.

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SKGQA, a Peptide Derived from the ANA/BTG3 Protein, Cleaves Amyloid-β with Proteolytic Activity.

Biomolecules

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Biomolecules

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