Spatial analysis of recurrent glioblastoma reveals perivascular niche organization.

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作者： Ugoma,Onubogu ^[1] ; Chandler D,Gatenbee ^[2] ; Sandhya,Prabhakaran ^[2] ; Kelsey L,Wolfe ^[1] ; Benjamin,Oakes ^[3] ; Roberto,Salatino ^[1] ; Rachael,Vaubel ^[4] ; Oszkar,Szentirmai ^[5] ; Alexander Ra,Anderson ^[2] ; Michalina,Janiszewska ^[1]

作者单位： The Skaggs Graduate School of Chemical and Biological Science, The Scripps Research Institute, La Jolla, California, USA.;Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida, USA. ^[1] Department of Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA. ^[2] Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida, USA. ^[3] Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, Rochester, Minnesota, USA. ^[4] Center for Neurological Surgery and Neuroscience, Cleveland Clinic Martin Health, Port St. Lucie, Florida, USA. ^[5]

关键词 Brain cancer Macrophages Molecular pathology Oncology

主题词胶质母细胞瘤(Glioblastoma);人类(Humans);肿瘤微环境(Tumor Microenvironment);脑肿瘤(Brain Neoplasms);肿瘤复发, 局部(Neoplasm Recurrence, Local);细胞外基质(Extracellular Matrix);男(雄)性(Male);巨噬细胞(Macrophages);女(雌)性(Female);末端转移酶端粒(Telomerase);单细胞分析(Single-Cell Analysis);突变(Mutation);中年人(Middle Aged)

DOI 10.1172/jci.insight.179853

PMID 38805346

发布时间 2024-09-11

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2024年9卷12期

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Spatial analysis of recurrent glioblastoma reveals perivascular niche organization.

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Spatial analysis of recurrent glioblastoma reveals perivascular niche organization.

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