Notoginseng leaf triterpenes promotes angiogenesis by activating the Nrf2 pathway and AMPK/SIRT1-mediated PGC-1/ERα axis in ischemic stroke.

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作者： Lei,Wang ^[1] ; Na,Qin ^[2] ; Shanchun,Ge ^[3] ; Xinyue,Zhao ^[2] ; Yuxi,Yang ^[2] ; Wanqi,Jia ^[2] ; Rongjian,Xu ^[4] ; Ting,Zhu ^[5]

作者单位： Institute of Neuroregeneration and Neurorehabilitation, Department of Pathophysiology, School of Basic Medicine, Qingdao University, Qingdao 266071, PR China; School of traditional Chinese pharmacy, China Pharmaceutical University, Nanjing 210009, PR China. ^[1] Institute of Neuroregeneration and Neurorehabilitation, Department of Pathophysiology, School of Basic Medicine, Qingdao University, Qingdao 266071, PR China. ^[2] School of traditional Chinese pharmacy, China Pharmaceutical University, Nanjing 210009, PR China. ^[3] Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, PR China. Electronic address: xurongjian@qdu.edu.cn. ^[4] Institute of Neuroregeneration and Neurorehabilitation, Department of Pathophysiology, School of Basic Medicine, Qingdao University, Qingdao 266071, PR China. Electronic address: zhuting0402@126.com. ^[5]

关键词 Angiogenesis Ischemic stroke Neurological restoration Notoginseng leaf triterpenes (PNGL)Oxidative stress