LC-MS/MS analysis of didehydrostemofoline from Stemona collinsiae roots extracts in rats plasma and pharmacokinetics profile after oral administration.

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第一作者： Norinee,Arlee

第一单位： Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Thailand.

作者： Norinee,Arlee ^[1] ; Sumate,Ampawong ^[2] ; Yanin,Limpanont ^[3] ; Kuntarat,Arunrungvichian ^[4] ; Sumet,Kongkiatpaiboon ^[5] ; Urusa,Thaenkhum ^[6]

作者单位： Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Thailand. ^[1] Department of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, Thailand. ^[2] Department of Social and Environmental Medicine, Faculty of Tropical Medicine, Mahidol University, Thailand. ^[3] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University, Thailand. ^[4] Drug Discovery and Development Center, Office of Advanced Science and Technology, Thammasat University (Rangsit Campus), Pathum Thani 12121, Thailand; Thammasat University Research Unit in Cannabis and Herbal Products Innovation, Thammasat University (Rangsit Campus), Pathum Thani 12121, Thailand. Electronic address: sumet_k@tu.ac.th. ^[5] Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Thailand. Electronic address: urusa.tha@mahidol.ac.th. ^[6]

关键词 Didehydrostemofoline Gnathostomiasis LC-MS/MS Pharmacokinetics Stemona collinsiae Stemonaceae