Bactericidal effectors of the <i>Stenotrophomonas maltophilia</i> type IV secretion system: functional definition of the nuclease TfdA and structural determination of TfcB.

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作者： Brandi L,Cobe ^[1] ; Supratim,Dey ^[2] ; George,Minasov ^[2] ; Nicole,Inniss ^[2] ; Karla J F,Satchell ^[2] ; Nicholas P,Cianciotto ^[1]

作者单位： Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. ^[1] Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.;Center for Structural Biology of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. ^[2]

关键词 DNase GHH nuclease Stenotrophomonas maltophilia T4SS antibacterial effectors bactericidal activity chitinase interbacterial competition peptidoglycan hydrolase

主题词嗜麦芽窄食单胞菌(Stenotrophomonas maltophilia);细菌蛋白质类(Bacterial Proteins);铜绿假单胞菌(Pseudomonas aeruginosa);大肠杆菌(Escherichia coli);蛋白质构象(Protein Conformation)

DOI 10.1128/mbio.01198-24

PMID 38832773

发布时间 2024-08-05

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