Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics.
第一作者:
Felix,Korell
第一单位:
Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center, Charlestown, MA 02129, USA.;Harvard Medical School, Boston, MA 02115, USA.;Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
作者:
医学主题词
人类(Humans);动物(Animals);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);磺胺类(Sulfonamides);细胞凋亡(Apoptosis);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);小鼠(Mice);T淋巴细胞(T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);免疫疗法, 过继(Immunotherapy, Adoptive);bcl-X蛋白质(bcl-X Protein);肽碎片(Peptide Fragments);原癌基因蛋白质类(Proto-Oncogene Proteins)
DOI
10.1126/scitranslmed.adk7640
PMID
38838132
发布时间
2026-03-06
基金项目
R01 CA249062/CA/NCI NIH HHS/United States
T32 GM144273/GM/NIGMS NIH HHS/United States
- 浏览1
Science translational medicine
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