DNA-based ForceChrono probes for deciphering single-molecule force dynamics in living cells.

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第一作者： Yuru,Hu

第一单位： The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province 430072, China.

作者： Yuru,Hu ^[1] ; Hongyun,Li ^[2] ; Chen,Zhang ^[1] ; Jingjing,Feng ^[1] ; Wenxu,Wang ^[1] ; Wei,Chen ^[1] ; Miao,Yu ^[1] ; Xinping,Liu ^[1] ; Xinghua,Zhang ^[3] ; Zheng,Liu ^[4]

作者单位： The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province 430072, China. ^[1] The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province 430072, China. Electronic address: hongyun77@whu.edu.cn. ^[2] The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province 430072, China. Electronic address: zhxh@whu.edu.cn. ^[3] The Institute for Advanced Studies, TaiKang Center for Life and Medical Sciences, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei Province 430072, China. Electronic address: zheng.liu@whu.edu.cn. ^[4]

关键词 catch bond force duration integrin force ligand density loading rate mechanotransduction molecular tension probes single-molecule force imaging single-molecule force spectroscopy vinculin