Assessing the impact of extracellular matrix fiber orientation on breast cancer cellular metabolism.

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第一作者： Madison R,Pickett

第一单位： Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA. mrpickett@uexas.edu.

作者： Madison R,Pickett ^[1] ; Yuan-I,Chen ^[2] ; Mohini,Kamra ^[2] ; Sachin,Kumar ^[3] ; Nikhith,Kalkunte ^[2] ; Gabriella P,Sugerman ^[2] ; Kelsey,Varodom ^[2] ; Manuel K,Rausch ^[4] ; Janet,Zoldan ^[2] ; Hsin-Chin,Yeh ^[5] ; Sapun H,Parekh ^[6]

作者单位： Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA. mrpickett@uexas.edu. ^[1] Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA. ^[2] Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA.;Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, 110016, India. ^[3] Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA.;Department of Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, 78712, Austin, TX, USA.;Department of Mechanical Engineering, The University of Texas at Austin, 78712, Austin, TX, USA.;Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, 78712, Austin, TX, USA. ^[4] Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA.;Texas Materials Institute, The University of Texas at Austin, Austin, TX, USA. ^[5] Department of Biomedical Engineering, The University of Texas at Austin, 107 W Dean Keeton Street Stop C0800, Austin, TX, 78712, USA. sparekh@utexas.edu. ^[6]

关键词 Breast cancer microenvironment Cellular metabolism Epithelial-to-mesenchymal transition (EMT)Extracellular matrix (ECM)Fluorescence lifetime imaging microscopy (FLIM)Optical redox ratio (ORR)

DOI 10.1186/s12935-024-03385-3

PMID 38840117

发布时间 2025-01-04

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