BIGH3 mediates apoptosis and gap junction failure in osteocytes during renal cell carcinoma bone metastasis progression.

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第一作者： Tianhong,Pan

第一单位： Departments of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

作者： Tianhong,Pan ^[1] ; Fengshuo,Liu ^[2] ; Xiaoxin,Hao ^[2] ; Shubo,Wang ^[3] ; Murtaza,Wasi ^[3] ; Jian H,Song ^[4] ; Valerae O,Lewis ^[1] ; Patrick P,Lin ^[1] ; Bryan,Moon ^[1] ; Justin E,Bird ^[1] ; Theocharis,Panaretakis ^[4] ; Sue-Hwa,Lin ^[5] ; Danielle,Wu ^[6] ; Mary C,Farach-Carson ^[7] ; Liyun,Wang ^[3] ; Ningyan,Zhang ^[8] ; Zhiqiang,An ^[8] ; Xiang H-F,Zhang ^[9] ; Robert L,Satcher ^[10]

作者单位： Departments of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ^[1] Departments of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. ^[2] Department of Mechanical Engineering, University of Delaware, Newark, DE, USA. ^[3] Departments of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ^[4] Departments of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Departments of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ^[5] Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX, USA; Departments of Bioengineering, Rice University, Houston, TX, USA. ^[6] Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX, USA; Departments of BioSciences, Rice University, Houston, TX, USA; Departments of Bioengineering, Rice University, Houston, TX, USA. ^[7] The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, USA. ^[8] Departments of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Departments of Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA; Departments of Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA; Departments of McNair Medical Institute, Baylor College of Medicine, Houston, TX, USA. ^[9] Departments of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: rlsatcher@mdanderson.org. ^[10]

关键词 Apoptosis BIGH3/TGFBI Bone metastasis Osteocyte Renal cell carcinoma