Charge-switchable cell-penetrating peptides for rerouting nanoparticles to glioblastoma treatment.

导出 LinkOut

翻译打印收藏纠错

作者： Maria,Mendes ^[1] ; Sandra,Nunes ^[2] ; Tânia,Cova ^[2] ; Francisco,Branco ^[3] ; Michael,Dyrks ^[4] ; Beate,Koksch ^[4] ; Nuno,Vale ^[5] ; João,Sousa ^[1] ; Alberto,Pais ^[2] ; Carla,Vitorino ^[6]

作者单位： Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, Coimbra 3000-548, Portugal; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Faculty of Sciences and Technology, University of Coimbra, Coimbra 3004-535, Portugal. ^[1] Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Faculty of Sciences and Technology, University of Coimbra, Coimbra 3004-535, Portugal. ^[2] Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, Coimbra 3000-548, Portugal. ^[3] Freie Universität Berlin, Institute of Chemistry and Biochemistry, Arnimallee 20, Berlin 14195, Germany. ^[4] PerMed Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal; CINTESIS@RISE, Faculty of Medicine, University of Porto (FFUP), Alameda Professor Hernâni Monteiro, Porto 4200-319, Portugal; Department of Community Medicine, Health Information and Decision (MEDCIDS), Faculty of Medicine, University of Porto, Rua Doutor Plácido da Costa, Porto 4200-450, Portugal. ^[5] Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, Coimbra 3000-548, Portugal; Coimbra Chemistry Centre, Institute of Molecular Sciences - IMS, Faculty of Sciences and Technology, University of Coimbra, Coimbra 3004-535, Portugal. Electronic address: csvitorino@ff.uc.pt. ^[6]

关键词 Blood-brain barrier Cell-penetrating peptides Glioblastoma Tumor-targeting peptides Ultra-small nanostructured lipid carriers