Sanggenol L induces ferroptosis in non-small cell lung cancer cells via regulating the miR-26a-1-3p/MDM2/p53 signaling pathway.

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作者： Rong,Fu ^[1] ; Yujie,You ^[1] ; Yuqing,Wang ^[2] ; Jue,Wang ^[3] ; Yu,Lu ^[1] ; Rui,Gao ^[1] ; Min,Pang ^[4] ; Peng,Yang ^[5] ; Hailong,Wang ^[6]

作者单位： School of Basic Medical Sciences, Shanxi Medical University, Taiyuan 030001, China. ^[1] Institute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China. ^[2] Department of Prosthodontics, First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China. ^[3] Department of Pulmonary and Critical Care Medicine, The First Hospital, Shanxi Medical University, Shanxi Province Key Laboratory of Respiratory Disease, Taiyuan, China. Electronic address: pangmin2009@126.com. ^[4] Institute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education, Shanxi University, Taiyuan 030006, China. Electronic address: peng114011@sxu.edu.cn. ^[5] School of Basic Medical Sciences, Shanxi Medical University, Taiyuan 030001, China. Electronic address: longwty@163.com. ^[6]

关键词 Ferroptosis MDM2 NSCLC Sanggenol L miR-26a-1-3p

主题词人类(Humans);微RNAs(MicroRNAs);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);原癌基因蛋白质c-mdm2(Proto-Oncogene Proteins c-mdm2);动物(Animals);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);肺肿瘤(Lung Neoplasms);小鼠(Mice);信号传导(Signal Transduction);小鼠, 裸(Mice, Nude);细胞系, 肿瘤(Cell Line, Tumor);小鼠, 近交BALB C(Mice, Inbred BALB C);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);男(雄)性(Male);女(雌)性(Female)

DOI 10.1016/j.bcp.2024.116345

PMID 38852643

发布时间 2024-09-10

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Biochemical pharmacology

2024年226卷

116345页

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Sanggenol L induces ferroptosis in non-small cell lung cancer cells via regulating the miR-26a-1-3p/MDM2/p53 signaling pathway.

Biochemical pharmacology

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Biochemical pharmacology

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Sanggenol L induces ferroptosis in non-small cell lung cancer cells via regulating the miR-26a-1-3p/MDM2/p53 signaling pathway.

Biochemical pharmacology

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Biochemical pharmacology

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