首页> Stem cell research & therapy> Fetal liver CD34<sup>+</sup> contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice.

Fetal liver CD34<sup>+</sup> contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice.

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第一作者： Teja,Celhar

第一单位： Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Singapore, 138648, Republic of Singapore. teja_celhar@IDlabs.a-star.edu.sg.;Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan. teja_celhar@IDlabs.a-star.edu.sg.;A*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #05-13, Singapore, 138648, Republic of Singapore. teja_celhar@IDlabs.a-star.edu.sg.

作者： Teja,Celhar ^[1] ; Xinyi,Li ^[2] ; Yunqian,Zhao ^[3] ; Hui Chien,Tay ^[3] ; Andrea,Lee ^[4] ; Hui Hua,Liew ^[5] ; Edwin Kunxiang,Shepherdson ^[5] ; Ravisankar,Rajarethinam ^[6] ; Yiping,Fan ^[7] ; Anselm,Mak ^[8] ; Jerry Kok Yen,Chan ^[7] ; Amit,Singhal ^[9] ; Takeshi,Takahashi ^[10]

作者单位： Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Singapore, 138648, Republic of Singapore. teja_celhar@IDlabs.a-star.edu.sg.;Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan. teja_celhar@IDlabs.a-star.edu.sg.;A*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #05-13, Singapore, 138648, Republic of Singapore. teja_celhar@IDlabs.a-star.edu.sg. ^[1] Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Singapore, 138648, Republic of Singapore.;Interdisciplinary Life Sciences, Purdue University, West Lafayette, IN, 47907, USA. ^[2] Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Singapore, 138648, Republic of Singapore. ^[3] Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Singapore, 138648, Republic of Singapore.;A*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #05-13, Singapore, 138648, Republic of Singapore. ^[4] Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, 229899, Republic of Singapore. ^[5] Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore. ^[6] Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, 229899, Republic of Singapore.;Obstetrics and Gynaecology Academic Clinical Programme, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.;Experimental Fetal Medicine Group, Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University Health System, Singapore, 117597, Republic of Singapore. ^[7] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.;Division of Rheumatology, University Medicine Cluster, National University Health System, Singapore, Republic of Singapore. ^[8] Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Singapore, 138648, Republic of Singapore.;A*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #05-13, Singapore, 138648, Republic of Singapore.;Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 636921, Republic of Singapore. ^[9] Central Institute for Experimental Animals (CIEA), 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan. ^[10]

关键词 Allogeneic tumor rejection Cord blood CD34 Endothelial disfunction Fetal liver CD34 Graft-versus-tumor HSPC Humanized mice LSEC Sinusoidal dilatation