The non-catalytic domains of O-GlcNAc cycling enzymes present new opportunities for function-specific control.

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第一作者： Chia-Wei,Hu

第一单位： School of Pharmacy, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA.

作者： Chia-Wei,Hu ^[1] ; Ke,Wang ^[1] ; Jiaoyang,Jiang ^[2]

作者单位： School of Pharmacy, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA. ^[1] School of Pharmacy, University of Wisconsin-Madison, 777 Highland Ave, Madison, WI 53705, USA. Electronic address: jiaoyang.jiang@wisc.edu. ^[2]

关键词 Function-specific modulator Non-catalytic domain O-GlcNAc transferase (OGT)O-GlcNAcase (OGA)

主题词 N-乙酰氨基葡糖转移酶类(N-Acetylglucosaminyltransferases);人类(Humans);乙酰葡萄糖胺(Acetylglucosamine);β-N-乙酰氨基己糖苷酶类(beta-N-Acetylhexosaminidases);底物特异性(Substrate Specificity);动物(Animals);糖基化(Glycosylation)

DOI 10.1016/j.cbpa.2024.102476

PMID 38861851

发布时间 2024-08-18

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