BUB1 regulates non-homologous end joining pathway to mediate radioresistance in triple-negative breast cancer.

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第一作者： Sushmitha,Sriramulu

第一单位： Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health, 1 Ford Place, Detroit, 5D-42, MI-48202, USA.

作者： Sushmitha,Sriramulu ^[1] ; Shivani,Thoidingjam ^[1] ; Wei-Min,Chen ^[2] ; Oudai,Hassan ^[3] ; Farzan,Siddiqui ^[4] ; Stephen L,Brown ^[4] ; Benjamin,Movsas ^[4] ; Michael D,Green ^[5] ; Anthony J,Davis ^[2] ; Corey,Speers ^[6] ; Eleanor,Walker ^[4] ; Shyam,Nyati ^[7]

作者单位： Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health, 1 Ford Place, Detroit, 5D-42, MI-48202, USA. ^[1] Department of Radiation Oncology, UT Southwestern Medical School, Dallas, TX-75390, USA. ^[2] Department of Surgical Pathology, Henry Ford Cancer Institute, Henry Ford Health, Detroit, MI-48202, USA. ^[3] Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health, 1 Ford Place, Detroit, 5D-42, MI-48202, USA.;Henry Ford Health + Michigan State University Health Sciences, Detroit, MI-48202, USA.;Department of Radiology, Michigan State University, East Lansing, MI-48824, USA. ^[4] Department of Radiation Oncology, University of Michigan, Ann Arbor, MI-48109, USA. ^[5] Department of Radiation Oncology, University of Michigan, Ann Arbor, MI-48109, USA.;Department of Radiation Oncology, UH Seidman Cancer Center, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH-44106, USA. ^[6] Department of Radiation Oncology, Henry Ford Cancer Institute, Henry Ford Health, 1 Ford Place, Detroit, 5D-42, MI-48202, USA. snyati1@hfhs.org.;Henry Ford Health + Michigan State University Health Sciences, Detroit, MI-48202, USA. snyati1@hfhs.org.;Department of Radiology, Michigan State University, East Lansing, MI-48824, USA. snyati1@hfhs.org. ^[7]

关键词 BUB1 DNA damage response DNAPK NHEJ Radiation sensitization TNBC