No improvement in mortality among critically ill patients with carbapenems as initial empirical therapy and more detection of multi-drug resistant pathogens associated with longer use: a post hoc analysis of a prospective cohort study.

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第一作者： Junki,Ishii

第一单位： Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

作者： Junki,Ishii ^[1] ; Mitsuaki,Nishikimi ^[2] ; Liesbet,De Bus ^[3] ; Jan,De Waele ^[3] ; Akihiro,Takaba ^[4] ; Akira,Kuriyama ^[5] ; Atsuko,Kobayashi ^[6] ; Chie,Tanaka ^[7] ; Hideki,Hashi ^[8] ; Hideki,Hashimoto ^[9] ; Hiroshi,Nashiki ^[10] ; Mami,Shibata ^[11] ; Masafumi,Kanamoto ^[12] ; Masashi,Inoue ^[13] ; Satoru,Hashimoto ^[14] ; Shinshu,Katayama ^[15] ; Shinsuke,Fujiwara ^[16] ; Shinya,Kameda ^[17] ; Shunsuke,Shindo ^[18] ; Tetsuya,Komuro ^[19] ; Toshiomi,Kawagishi ^[20] ; Yasumasa,Kawano ^[21] ; Yoshihito,Fujita ^[22] ; Yoshiko,Kida ^[1] ; Yuya,Hara ^[23] ; Hideki,Yoshida ^[24] ; Shigeki,Fujitani ^[24] ; Nobuaki,Shime ^[1] ; DIANA study Japanese group

作者单位： Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. ^[1] Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.;Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan. ^[2] Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.;Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. ^[3] JA Hiroshima General Hospital, Hiroshima, Japan. ^[4] Emergency and Critical Care Center, Kurashiki Central Hospital, Okayama, Japan. ^[5] Takarazuka City Hospital, Hyogo, Japan. ^[6] Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan. ^[7] Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan. ^[8] Hitachi General Hospital, Ibaraki, Japan. ^[9] Iwate Prefectural Central Hospital, Iwate, Japan. ^[10] Department of Emergency and Critical Care Medicine, Wakayama Medical University Hospital, Wakayama, Japan. ^[11] Department of Anesthesiology, Gunma Prefectural Cardiovascular Center, , Gunma, Japan. ^[12] Department of Anesthesiology, Nagoya City University Hospital, Aichi, Japan. ^[13] Non-Profit Organization ICU Collaboration Network (ICON), Tokyo, Japan. ^[14] Division of Intensive Care, Department of Anesthesiology and Intensive Care Medicine, Jichi Medical University School of Medicine, Tochigi, Japan. ^[15] National Hospital Organization Ureshino Medical Center, Saga, Japan. ^[16] Jikei University School of Medicine Hospital, Tokyo, Japan. ^[17] Omori Red Cross Hospital, Tokyo, Japan. ^[18] Department of General Internal Medicine, TMG Muneoka Central Hospital, Saitama, Japan. ^[19] Toyama University Hospital, Toyama, Japan. ^[20] Fukuoka University Hospital, Fukuoka, Japan. ^[21] Aichi Medical University Hospital, Aichi, Japan. ^[22] Yodogawa Christian Hospital, Osaka, Japan. ^[23] Department of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Kanagawa, Japan. ^[24]

关键词 carbapenem critically ill infectious disease initial empirical therapy intensive care unit multidrug resistance

主题词人类(Humans);卡巴配能类(Carbapenems);危重病(Critical Illness);男(雄)性(Male);前瞻性研究(Prospective Studies);女(雌)性(Female);抗药性, 多种, 细菌(Drug Resistance, Multiple, Bacterial);老年人(Aged);抗菌药(Anti-Bacterial Agents);中年人(Middle Aged);重症监护病房(Intensive Care Units);细菌感染(Bacterial Infections);日本(Japan);老年人, 80以上(Aged, 80 and over);细菌(Bacteria)

DOI 10.1128/spectrum.00342-24

PMID 38864641

发布时间 2024-10-11

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Microbiology spectrum

2024年12卷7期

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No improvement in mortality among critically ill patients with carbapenems as initial empirical therapy and more detection of multi-drug resistant pathogens associated with longer use: a post hoc analysis of a prospective cohort study.

Microbiology spectrum

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No improvement in mortality among critically ill patients with carbapenems as initial empirical therapy and more detection of multi-drug resistant pathogens associated with longer use: a post hoc analysis of a prospective cohort study.

Microbiology spectrum

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Microbiology spectrum

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