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Proteolysis-free amoeboid migration of melanoma cells through crowded environments via bleb-driven worrying.

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第一作者： Meghan K,Driscoll

第一单位： Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

作者： Meghan K,Driscoll ^[1] ; Erik S,Welf ^[1] ; Andrew,Weems ^[1] ; Etai,Sapoznik ^[1] ; Felix,Zhou ^[1] ; Vasanth S,Murali ^[1] ; Juan Manuel,García-Arcos ^[2] ; Minna,Roh-Johnson ^[3] ; Matthieu,Piel ^[2] ; Kevin M,Dean ^[1] ; Reto,Fiolka ^[4] ; Gaudenz,Danuser ^[5]

作者单位： Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. ^[1] Institut Curie, UMR144, CNRS, PSL University, Paris, France. ^[2] Department of Biochemistry, School of Medicine, University of Utah, Salt Lake City, UT 84113, USA. ^[3] Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: reto.fiolka@utsouthwestern.edu. ^[4] Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: gaudenz.danuser@utsouthwestern.edu. ^[5]

关键词 amoeboid blebbing cell migration computer vision extracellular matrix remodeling fluorescence microscopy light-sheet microscopy macropinocytosis melanoma