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Targeted-delivery of nanomedicine-enabled methylprednisolone to injured spinal cord promotes neuroprotection and functional recovery after acute spinal cord injury in rats.

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第一作者： Wei,Zhao

第一单位： Spinal Cord Damage Research Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.

作者： Wei,Zhao ^[1] ; Zhenshan,Jia ^[2] ; William A,Bauman ^[3] ; Yiwen,Qin ^[4] ; Yuanzhen,Peng ^[5] ; Zihao,Chen ^[6] ; Christopher P,Cardozo ^[7] ; Dong,Wang ^[8] ; Weiping,Qin ^[9]

作者单位： Spinal Cord Damage Research Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA. ^[1] Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA. ^[2] Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA; Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, USA. ^[3] Spinal Cord Damage Research Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA; GCM Grosvenor, New York, USA. ^[4] Spinal Cord Damage Research Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA. ^[5] Departments of Biotechnology, Brown University, Providence, RI, USA. ^[6] Spinal Cord Damage Research Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA; Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, USA. ^[7] Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: dwang@unmc.edu. ^[8] Spinal Cord Damage Research Center, James J. Peters Veterans Affairs Medical Center, Bronx, New York, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address: weiping.qin@mssm.edu. ^[9]

关键词 Functional outcomes Methylprednisolone Nanomedicine Neuroprotection Spinal cord injury