Dynamical and combinatorial coding by MAPK p38 and NFκB in the inflammatory response of macrophages.

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作者： Stefanie,Luecke ^[1] ; Xiaolu,Guo ^[1] ; Katherine M,Sheu ^[1] ; Apeksha,Singh ^[1] ; Sarina C,Lowe ^[2] ; Minhao,Han ^[1] ; Jessica,Diaz ^[1] ; Francisco,Lopes ^[3] ; Roy,Wollman ^[4] ; Alexander,Hoffmann ^[5]

作者单位： Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California Los Angeles, Los Angeles, CA, 90095, USA.;Institute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, 90095, USA. ^[1] Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California Los Angeles, Los Angeles, CA, 90095, USA.;Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA. ^[2] Institute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, 90095, USA.;Grupo de Biologia do Desenvolvimento e Sistemas Dinamicos, Campus Duque de Caxias Professor Geraldo Cidade, Universidade Federal do Rio de Janeiro, Duque de Caxias, 25240-005, Brazil. ^[3] Institute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, 90095, USA.;Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA, 90095, USA.;Department of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, 90095, USA. ^[4] Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California Los Angeles, Los Angeles, CA, 90095, USA. ahoffmann@ucla.edu.;Institute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, 90095, USA. ahoffmann@ucla.edu. ^[5]

关键词 Combinatorial Signaling Dynamics Cytokine Control Inflammation Innate Immunity Signal Encoding