Macrophages exploit the mannose receptor and JAK-STAT1-MHC-II pathway to drive antigen presentation and the antimycobacterial immune response after BCG vaccination.
第一作者:
Ying,Zhang
第一单位:
Department of Immunology, Wuhan University Taikang Medical School (School of Basic Medical Sciences), Department of Allergy of Zhongnan Hospital and Hubei Province Key Laboratory of Allergy and Immunology, Wuhan University, Wuhan 430071, China.;State Key Laboratory of Virology, Medical Research Institute and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan 430071, China.
作者:
医学主题词
动物(Animals);卡介苗(BCG Vaccine);STAT1转录因子(STAT1 Transcription Factor);巨噬细胞(Macrophages);抗原呈递(Antigen Presentation);小鼠(Mice);甘露糖结合凝集素类(Mannose-Binding Lectins);小鼠, 近交C57BL(Mice, Inbred C57BL);外源凝集素类, C型(Lectins, C-Type);结核分枝杆菌(Mycobacterium tuberculosis);Janus激酶类(Janus Kinases);受体, 细胞表面(Receptors, Cell Surface);信号传导(Signal Transduction);组织相容性抗原Ⅱ类(Histocompatibility Antigens Class II);结核(Tuberculosis);接种(Vaccination);小鼠, 基因敲除(Mice, Knockout);女(雌)性(Female)
DOI
10.3724/abbs.2024100
PMID
38894685
发布时间
2024-10-08
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Acta biochimica et biophysica Sinica
2024年56卷8期
1130-1144页
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