Insulin signaling accelerates the anterograde movement of Rab4 vesicles in axons through Klp98A/KIF16B recruitment via Vps34-PI3Kinase.

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作者： Kamaldeep,Singh ^[1] ; Semanti,Das ^[2] ; Sabyasachi,Sutradhar ^[1] ; Jonathon,Howard ^[2] ; Krishanu,Ray ^[2]

作者单位： Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai - 400005, India. ^[1] Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT - 06520, United States. ^[2] National Brain Research Centre, Manesar, Haryana - 122051, India. ^[3]

关键词 Klp98A Rab4 vesicles Vps34 axonal transport insulin signaling kinesin neurodegeneration phosphoinositide-3-phosphate [PI(3)P]recycling endosomes synaptic homeostasis

DOI 10.1101/2024.04.24.590898

PMID 38895253

发布时间 2024-06-24

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Insulin signaling accelerates the anterograde movement of Rab4 vesicles in axons through Klp98A/KIF16B recruitment via Vps34-PI3Kinase.

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Insulin signaling accelerates the anterograde movement of Rab4 vesicles in axons through Klp98A/KIF16B recruitment via Vps34-PI3Kinase.

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