Democratizing protein language models with parameter-efficient fine-tuning.

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作者： Samuel,Sledzieski ^[1] ; Meghana,Kshirsagar ^[2] ; Minkyung,Baek ^[1] ; Rahul,Dodhia ^[3] ; Juan,Lavista Ferres ^[1] ; Bonnie,Berger ^[1]

作者单位： AI for Good Research Lab, Microsoft Corporation, Redmond, WA 98052. ^[1] Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139. ^[2] Department of Biological Sciences, Seoul National University, Seoul 08826, South Korea. ^[3] Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139. ^[4]

关键词 homooligomer symmetry parameter-efficient fine-tuning protein language models protein–protein interactions quaternary structure

主题词蛋白质组学(Proteomics);蛋白质类(Proteins);自然语言处理(Natural Language Processing);蛋白质相互作用图谱(Protein Interaction Mapping);计算生物学(Computational Biology);人类(Humans);算法(Algorithms)

DOI 10.1073/pnas.2405840121

PMID 38900798

发布时间 2024-07-08

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