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Palmitic acid induces β-cell ferroptosis by activating ceramide signaling pathway.

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第一作者： Maojun,Guo

第一单位： Department of Endocrinology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.

作者： Maojun,Guo ^[1] ; Xiaolong,Huang ^[1] ; Junhan,Zhang ^[1] ; Ying,Huang ^[1] ; Ying,Tang ^[1] ; Honghua,Wen ^[1] ; Yanan,Xu ^[2] ; Shaokun,Zhang ^[3] ; Xiao,Wei ^[4] ; Shuoshuo,Sun ^[5] ; Qun,Zhu ^[6]

作者单位： Department of Endocrinology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China. ^[1] Department of Endocrinology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China; Department of Endocrinology, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, 222002, China. ^[2] Department of Endocrinology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China; Department of Infectious Diseases, Taizhou Second People's Hospital, Taizhou, Jiangsu, 225500, China. ^[3] Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, China. ^[4] The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. ^[5] Department of Endocrinology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China. Electronic address: zhuqun@njmu.edu.cn. ^[6]

关键词 Ceramide Ferroptosis Palmitic acid c-Jun N-terminal kinase β-cell