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In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer.

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第一作者： Sebastien,Martinez

第一单位： Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

作者： Sebastien,Martinez ^[1] ; Shifei,Wu ^[2] ; Michael,Geuenich ^[2] ; Ahmad,Malik ^[2] ; Ramona,Weber ^[3] ; Tristan,Woo ^[4] ; Amy,Zhang ^[5] ; Gun Ho,Jang ^[5] ; Dzana,Dervovic ^[1] ; Khalid N,Al-Zahrani ^[1] ; Ricky,Tsai ^[1] ; Nassima,Fodil ^[6] ; Philippe,Gros ^[6] ; Steven,Gallinger ^[7] ; G Gregory,Neely ^[8] ; Faiyaz,Notta ^[9] ; Ataman,Sendoel ^[3] ; Kieran,Campbell ^[2] ; Ulrich,Elling ^[10] ; Daniel,Schramek ^[11]

作者单位： Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. ^[1] Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.;Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. ^[2] Institute for Regenerative Medicine (IREM), University of Zurich, Zurich, Switzerland. ^[3] Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. ^[4] PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, ON, Canada. ^[5] Department of Biochemistry, Dahdaleh Institute of Genomic Medicine, McGill University, Montreal, QC, Canada. ^[6] Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.;PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, ON, Canada. ^[7] Dr. John and Anne Chong Lab for Functional Genomics, Charles Perkins Centre, and School of Life and Environmental Sciences, The University of Sydney, Camperdown, NSW 2006, Australia. ^[8] Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.;PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, ON, Canada. ^[9] Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Dr. Bohr-Gasse 3, Vienna BioCenter (VBC), 1030, Vienna, Austria. ^[10] Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. schramek@lunenfeld.ca.;Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. schramek@lunenfeld.ca. ^[11]