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首页> International immunopharmacology> A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.

A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.

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作者： Jingyi,Zhang ^[1] ; Xuemei,Luo ^[2] ; Xian,Yang ^[3] ; Baoyan,Wang ^[3] ; Lufeng,Zheng ^[4] ; Simin,Yan ^[5]

作者单位： Department of Pharmacy, Nanjing Drum Tower Hospital, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210008, Jiangsu, China. ^[1] Nanjing Medical Center for Clinical Pharmacy, Nanjing 210008, Jiangsu, China; Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, Jiangsu, China. ^[2] Nanjing Medical Center for Clinical Pharmacy, Nanjing 210008, Jiangsu, China. ^[3] School of Life Science and Technology, China Pharmaceutical University, Nanjing 210008, Jiangsu, China. Electronic address: zhlf@cpu.edu.cn. ^[4] Nanjing Medical Center for Clinical Pharmacy, Nanjing 210008, Jiangsu, China; Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, Jiangsu, China. Electronic address: tmacsamyan@gmail.com. ^[5]

关键词 Cardiomyocytes hypertrophy FOXP3 Mitophagy Parkin SNHG1

主题词叉头转录因子类(Forkhead Transcription Factors);肌细胞, 心脏(Myocytes, Cardiac);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);动物(Animals);微RNAs(MicroRNAs);心脏扩大(Cardiomegaly);大鼠(Rats);人类(Humans);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);细胞, 培养的(Cells, Cultured)

DOI 10.1016/j.intimp.2024.112526

PMID 38908088

发布时间 2024-07-15

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