首页> Journal of pharmaceutical sciences> A Stratified Analysis of Supersaturation and Precipitation Effects Based on the Refined Developability Classification System (rDCS).

A Stratified Analysis of Supersaturation and Precipitation Effects Based on the Refined Developability Classification System (rDCS).

导出 LinkOut

翻译打印收藏纠错

第一作者： Kristian,Beran

第一单位： Fraunhofer Institute for Translational Medicine and Pharmacology, Frankfurt am Main, Germany; Janssen Pharmaceutica NV, Pharmaceutical & Material Sciences, Beerse, Belgium.

作者： Kristian,Beran ^[1] ; Eline,Hermans ^[2] ; René,Holm ^[3] ; Kia,Sepassi ^[4] ; Jennifer,Dressman ^[5]

作者单位： Fraunhofer Institute for Translational Medicine and Pharmacology, Frankfurt am Main, Germany; Janssen Pharmaceutica NV, Pharmaceutical & Material Sciences, Beerse, Belgium. ^[1] Janssen Pharmaceutica NV, Pharmaceutical & Material Sciences, Beerse, Belgium. ^[2] University of Southern Denmark, Department of Physics, Chemistry and Pharmacy, Odense, Denmark. ^[3] Janssen Research & Development, LLC, Discovery Pharmaceutics, San Diego, CA, USA. ^[4] Fraunhofer Institute for Translational Medicine and Pharmacology, Frankfurt am Main, Germany. Electronic address: Dressman@em.uni-frankfurt.de. ^[5]

关键词 Biopharmaceutical risk analysis Developability Formulation guidance Oral absorption Precipitation Refined developability classification system (rDCS)Supersaturation